mdmartin
02-11-2006, 12:11 PM
Hey all,
Just a quick question about the effects of Trenbolone and Masteron on hair loss.
I've recently been looking through posts on the SE board and doing a few internet searches regarding steroids and hair loss...I'm more confused now than I ever have been. I currently take finasteride on a daily basis and have been for quite some time now. I know that taking Nandrolone (Deca) is a no-no while on Finasteride but have read conflicting posts on the effects Trenbolone and Masteron have on hair loss. Does taking Finasteride with either of these two compounds speed up the process of going bald? I've done two cycles in the past, one with Testosterone Depot and Deca (prior to starting Finasteride), and the other with Testosterone Enanthate and Equipoise (while on Finasteride). I have had no problems with hair loss to date. I've put together a cutter that consists of Test Prop, Equipoise, and Trinabol and am now worried that Tren will wreak havoc with my hair. Which is the more hair-friendly compound to use while on Finasteride? Would it be better to use Masteron in place of Tren in the above-mentioned cycle?
Any help you might have would be appreciated.
Cheers,
MDM
Below is a copy of one of the articles that I was referring to...it was taken from EliteFitness.com.
Finasteride is a potent inhibitor of the 5-alpha reductase enzyme, specifically 5AR type II localized in the scalp and prostate. 1mg and 5mg doses have been shown to lower scalp concentrations of DHT by 64.1% and 69.4% respectively. Serum DHT levels also drop significantly with use, declining by 71.4% and 72.2% with the same doses. Understanding the strong action of DHT this amounts to a considerable reduction in androgenic activity, allowing finasteride to be quite effective at combating hair loss. In trials the drug was shown to be effective at enhancing hair growth in 66% of long term (2 years) treated men with androgenetic alopecia. This figure rises to 83% when we measure the group noting a halt in the recession of scalp hair. But the question at hand is will this success port over to the steroid-using athlete.
Testosterone is the principle target for 5AR, so finasteride does affect the dynamics of all testosterone preparations. The testosterone analogues methyltestosterone, fluoxymesterone (Halotestin®), methandrostenolone and boldenone also reduce to more potent steroids upon 5AR interaction. However this concludes the list of steroids that might call for the use of finasteride with hair-sensitive individuals. Methandrostenolone and boldenone in fact interact with 5-alpha reductase with extremely low affinity, so for all intents and purposed the benefit of finasteride with these drugs is likely insignificant.
Nandrolone and a few of its analogues also interact with 5-alpha reductase, however here this reduction is typically beneficial. Dihydronandrolone has a lower affinity for the androgen receptor than nandrolone; meaning here 5AR actually lowers the activity of this steroid in the scalp. The tendency is similar with ethylestrenol (Orabolin®), norethandrolone (Nilevar®) and trenbolone. What this basically means is that nandrolone and its analogues are typically slightly safer for hair loss than testosterone based drugs, in that they should exhibit greater activity in muscle tissue as compared to androgen target tissues such as the scalp due to this reduction. If we inhibit 5-alpha reductase with finasteride, we are inadvertently increasing scalp androgenicity.
Just a quick question about the effects of Trenbolone and Masteron on hair loss.
I've recently been looking through posts on the SE board and doing a few internet searches regarding steroids and hair loss...I'm more confused now than I ever have been. I currently take finasteride on a daily basis and have been for quite some time now. I know that taking Nandrolone (Deca) is a no-no while on Finasteride but have read conflicting posts on the effects Trenbolone and Masteron have on hair loss. Does taking Finasteride with either of these two compounds speed up the process of going bald? I've done two cycles in the past, one with Testosterone Depot and Deca (prior to starting Finasteride), and the other with Testosterone Enanthate and Equipoise (while on Finasteride). I have had no problems with hair loss to date. I've put together a cutter that consists of Test Prop, Equipoise, and Trinabol and am now worried that Tren will wreak havoc with my hair. Which is the more hair-friendly compound to use while on Finasteride? Would it be better to use Masteron in place of Tren in the above-mentioned cycle?
Any help you might have would be appreciated.
Cheers,
MDM
Below is a copy of one of the articles that I was referring to...it was taken from EliteFitness.com.
Finasteride is a potent inhibitor of the 5-alpha reductase enzyme, specifically 5AR type II localized in the scalp and prostate. 1mg and 5mg doses have been shown to lower scalp concentrations of DHT by 64.1% and 69.4% respectively. Serum DHT levels also drop significantly with use, declining by 71.4% and 72.2% with the same doses. Understanding the strong action of DHT this amounts to a considerable reduction in androgenic activity, allowing finasteride to be quite effective at combating hair loss. In trials the drug was shown to be effective at enhancing hair growth in 66% of long term (2 years) treated men with androgenetic alopecia. This figure rises to 83% when we measure the group noting a halt in the recession of scalp hair. But the question at hand is will this success port over to the steroid-using athlete.
Testosterone is the principle target for 5AR, so finasteride does affect the dynamics of all testosterone preparations. The testosterone analogues methyltestosterone, fluoxymesterone (Halotestin®), methandrostenolone and boldenone also reduce to more potent steroids upon 5AR interaction. However this concludes the list of steroids that might call for the use of finasteride with hair-sensitive individuals. Methandrostenolone and boldenone in fact interact with 5-alpha reductase with extremely low affinity, so for all intents and purposed the benefit of finasteride with these drugs is likely insignificant.
Nandrolone and a few of its analogues also interact with 5-alpha reductase, however here this reduction is typically beneficial. Dihydronandrolone has a lower affinity for the androgen receptor than nandrolone; meaning here 5AR actually lowers the activity of this steroid in the scalp. The tendency is similar with ethylestrenol (Orabolin®), norethandrolone (Nilevar®) and trenbolone. What this basically means is that nandrolone and its analogues are typically slightly safer for hair loss than testosterone based drugs, in that they should exhibit greater activity in muscle tissue as compared to androgen target tissues such as the scalp due to this reduction. If we inhibit 5-alpha reductase with finasteride, we are inadvertently increasing scalp androgenicity.